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There is a lot of talk about health care costs in the United States that is mostly centered on prescription medicine spending, overlooking the largest share of U.S. health care spending – hospital care. And hospital spending continues to grow as their prices increase.

Studies have shown hospitals mark up medicines up to 500% of their cost, with nearly one in five hospitals marking up medicine prices by 700% or more. But prescription medicines are just one piece of the hospital cost picture. Data recently featured by Axios point out how much more we spend on hospital care compared to retail prescription medicines.

Fact: The United States spends three times more per person on hospital care than on retail prescription medicines.

Hospital Care Chart5[2]

These data, coupled with a recent analysis from United Health Group, highlight how hospitals are the primary drivers of health care spending. United Health Group found that prices for inpatient care charged by hospitals increased significantly from 2013 to 2017, far surpassing prices paid to independent physicians for the same care. According to the analysis, hospital prices increased by 4.5% per year over this period while independent physician prices increased just 2.5%.

Rather than looking at one piece of the health care system, we need a robust discussion about the whole system and ways we can rein in health care spending. Looking at hospital costs is a critical place to start. Learn more at LetsTalkAboutCost.org.

Nicole Longo

Nicole Longo is Deputy Vice President of public affairs at PhRMA focusing on Medicare, 340B, importation and more. She previously worked for a D.C.-based public affairs firm where she assisted a wide range of clients with communications efforts on everything from trade policy to agriculture policy to health care policy. Outside the office, Nicole can be found trying new restaurants (usually Italian), taking an occasional barre class and cheering on the Cincinnati Bengals.

Nicole Longo

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ICYMI: Hospital consolidation is driving up health care costs

August 27, 2026

340B’s reality: A booming business for hospitals, pharmacies and corporate giants

June 25, 2026

A program off track: How 340B drives both hospital consolidation and system gaming

April 27, 2026

Washington Post Editorial Board says 340B has become “corporate welfare”

April 27, 2026

Hospitals drive nearly 80% of the U.S. health spending gap

March 25, 2026

Congress should look under the hood of 340B, hospitals don't want them to

March 19, 2026

340B hospitals buy low and sell high, a new analysis shows

March 12, 2026

New report from Minnesota: 340B is generating billions for big hospitals

March 9, 2026

Latest analysis from Ohio exposes growing abuses of the 340B markup program

July 7, 2025

By the Numbers: 340B continues to climb in profits, dwindle with patient support

September 13, 2023

New report: Hospitals mark up medicine prices 500%

August 2, 2023

read more

August 2, 2023

Nonprofit hospitals fall short on community benefit, studies show

April 24, 2023

Why Congress should prioritize fixing the 340B program

March 2, 2023

What they are saying: Nonprofit hospitals are gaming the system at the expense of patients

February 21, 2023

340B program continues to drive shift in care to more expensive hospital settings

December 15, 2022

New analysis confirms hospitals markup prices for oncology therapies

April 21, 2022

340B 101: Three charts show the program maximizes hospitals’ bottom line with little consideration for patients

February 8, 2022

To drive up profits, hospitals continue unnecessary medicine mark-ups, burdening patients, employers and health care system

October 14, 2021

340B hospitals among those that provide lowest levels of community benefit across the country

July 27, 2021

New data from insurers show detriments of copay accumulator adjustment programs

April 28, 2021

Getting the 340B program back on track in 2021

March 10, 2021

Nearly 40% of commercially insured patients face half their annual out-of-pocket expenses from just one health care encounter

March 2, 2021

Insurers shift medicine costs to patients with severe chronic illnesses

February 1, 2021

The new Administration should reconsider a recent HHS rule that could negatively impact patient access and affordability

January 27, 2021

New insulin report highlights how incentives benefit middlemen, harm patients

January 22, 2021

New data show retail medicine prices fell in 2019

January 13, 2021

Correcting the record: Biopharmaceutical companies remain committed to the 340B program and helping patients

December 17, 2020

Accumulator adjustment programs lead to surprise out-of-pocket costs and nonadherence, analysis finds

November 19, 2020

340B hospitals and for-profit pharmacies generating significant revenue from program meant to help needy patients

October 23, 2020

Study finds biopharmaceutical innovation is responsible for 35% of the increase in life expectancy from 1990 to 2015

October 21, 2020

Survey found insurance premiums grew faster than inflation in 2020

October 20, 2020

Study finds middlemen excluded nearly 850 medicines from formularies this year

September 17, 2020

Manufacturer cost-sharing assistance programs can save chronically ill patients hundreds to thousands of dollars annually

August 19, 2020

Commercial health plans have increased patients’ out-of-pocket costs by over 50% in some therapeutic areas

August 12, 2020

Commercial health plans transition from copays to coinsurance and deductibles has increased patient out-of-pocket costs

August 6, 2020

Four things to know about the IQVIA “Medicine Spending and Affordability in the U.S.” report

August 5, 2020

New data show commercially insured patients face increasingly high cost sharing for brand medicines

July 30, 2020

Payers subject 80% of new RA and MS patients to utilization management restrictions

July 22, 2020

Study finds the pharmaceutical industry retains a smaller share of revenue than research-intensive industries

July 14, 2020

ICYMI: Pharmacy benefit managers increasingly exclude medicines from formularies, restricting patient access

June 1, 2020

New rule makes it harder for patients to lower their out-of-pocket costs

May 20, 2020

ICYMI: Patients saved nearly $800,000 out of pocket through innovative contracting arrangements

April 20, 2020

Retail medicine spending to remain stable share of overall health care spending through next decade

April 16, 2020

PhRMA comments on HHS proposed rule on manufacturer cost-sharing assistance and accumulator adjustment programs

March 3, 2020

Addressing barriers that inhibit value-based contracts

February 21, 2020

Fact Check: HCCI analysis overstates medicine spending and prices

February 19, 2020

Cancer medicines cost twice as much at hospitals, study finds

January 21, 2020

New GAO report: Some hospitals participating in 340B may not be eligible for the program

January 14, 2020

Nearly 50% of brand medicine spending goes to the supply chain and others

January 9, 2020

New NHE data: Medicine prices declined, and hospitals were biggest driver of health care spending in 2018

December 6, 2019

More evidence that medicine prices are growing at slowest rate in decades

October 4, 2019

The truth about the marketing and promotion of medicines

October 3, 2019

Survey shows out-of-pocket costs top health care concern for voters

October 2, 2019

Hospitals make 9 times more than physicians’ offices on provider-administered medicines

September 10, 2019

340B Spotlight: How for-profit middlemen are taking advantage of a program meant to support nonprofit entities and patients

August 20, 2019

Three things to know about the Part D GAO report

August 16, 2019

Four states adopt first-in-the-nation laws to protect patients from surprise insurer practices

July 15, 2019

New Let’s Talk About Cost TV ad asks: Why aren’t patients sharing in savings at the pharmacy counter?

July 9, 2019

Study finds hospitals continue to mark up medicines up to 500% of their cost

July 9, 2019

Three reasons why the latest Rx Savings Solutions analysis is misleading

July 2, 2019

How the rebate rule would help reduce patients’ out-of-pocket costs

June 3, 2019

Fresh data show, yet again, 340B is growing while charity care dwindles at many 340B hospitals

May 16, 2019

New study finds hospitals continue to push patients to costlier outpatient settings

May 13, 2019

4 Things to know about the IQVIA “Medicine Use and Spending” report

May 9, 2019

Six policy solutions to help patients afford their insulin

April 9, 2019

PhRMA comments on OIG proposed rule to reform the rebate system

April 8, 2019

340B continues to drive shift in site of care for physician-administered medicines to more expensive hospital settings

April 5, 2019

Five key facts about the market for insulins

April 1, 2019

OIG proposed rule could help strengthen the Part D market

March 28, 2019

Rebate rule would help ensure seniors with diabetes don’t pay more for their medicine than their insurer

March 25, 2019

The PBM story you haven’t heard: Hidden fees quadrupled in two years

March 20, 2019

OptumRX: Sharing rebates with patients is “worth it”

March 18, 2019

New data show how sharing negotiated discounts could save certain patients hundreds of dollars at the pharmacy counter

February 25, 2019

What you need to know about the new NHE health spending projections

February 22, 2019

New study shows why insurers should share rebates with Medicare Part D beneficiaries on a mandatory basis

February 14, 2019

New IQVIA data show medicine prices grew just 1.5 percent in 2018

January 29, 2019

Health Affairs study misses the mark on medicine costs

January 28, 2019

New government data show medicine price growth continues to decline

January 18, 2019

10 things you should know about medicine spending and costs

January 2, 2019

New study finds hospitals prescribe more medicines, and more expensive medicines, after joining 340B program

December 18, 2018

Six key facts about the market for insulins

December 17, 2018

Americans want to know more than just the list price of a medicine—and we’re answering their call

October 15, 2018

What they are saying: PhRMA member executives on industry’s new approach to DTC television advertising

October 15, 2018

Coupons allow patients to remain on medicines in spite of high cost sharing and deductibles

October 4, 2018

New study finds some hospitals mark up medicine prices at least 700 percent

September 5, 2018

69 percent of patients abandon medicines when cost sharing is more than $250

August 23, 2018

New analysis finds 340B medicine sales hit record high in 2017 and continue to grow as a share of total drug spending

August 20, 2018

New analysis in Health Affairs reinforces one-third of medicine list price rebated back to supply chain

August 13, 2018

PhRMA submission to HHS on blueprint to lower drug prices and reduce out-of-pocket costs

July 16, 2018

GAO again recommends improvements to 340B program

July 11, 2018

New data show patients’ out-of-pocket costs are rising faster than their insurers’ costs

July 9, 2018

Pass-through rebates do not violate non-interference clause but they do increase savings for seniors

July 2, 2018

Patients with a deductible have seen their out-of-pocket costs for brand medicines increase 50 percent since 2014

June 20, 2018

ICYMI: Analysis finds higher outpatient drug spending at 340B hospitals

June 18, 2018

Sharing negotiated discounts at the pharmacy counter could save seniors with diabetes more than $350 annually

May 17, 2018

New 340B analysis: Hospitals raking in billions while uncompensated care drops by billions

May 15, 2018

Video: PhRMA CEO discusses biopharmaceutical supply chain at POLITICO event

May 4, 2018

Event tomorrow: Making the biopharmaceutical supply chain work for patients

May 2, 2018

Spending on medicines grew less than one percent in 2017

April 19, 2018

Patients pay the price when hospitals mark up cancer medicines

April 5, 2018

340B Spotlight: How much money are hospitals pocketing under 340B and what are they doing with those profits?

March 28, 2018

New Let’s Talk About Cost ads highlight how copay accumulator programs could leave patients financially exposed

March 27, 2018

Video: How does the supply chain shape brand-name medicine prices?

March 19, 2018

4 Things to know about the IQVIA 2018 and Beyond: Outlook and Turning Points report

March 13, 2018

ICYMI: Two PBM reports show dramatic slowdown in medicine spending growth

March 2, 2018

Copay coupons can help ease patients’ out-of-pocket costs

February 16, 2018

340B Spotlight: Hospital system adds voice to comments about flawed 340B program

February 2, 2018

PhRMA launches new consumer-facing Let’s Talk About Cost website

January 24, 2018

340B Spotlight: New pieces of legislation continue momentum to fix 340B program

January 18, 2018

NHE Data: Medicine spending grew just 1.3 percent in 2016

December 12, 2017

340B Spotlight: ICYMI – 340B hearing, new reports highlight growing need for program reform

October 20, 2017

How much are hospitals marking up the price of medicines? The answer may surprise you.

October 17, 2017

4 things to know about the QuintilesIMS drivers of medicine spending in the U.S. report

September 28, 2017

Video: PhRMA CEO discusses medicine costs with CNBC's Squawk Box

July 31, 2017

340B Spotlight: New analysis finds 340B program growth continues to accelerate despite false claims

July 13, 2017

340B Spotlight: ICYMI – AJC looks at how some Georgia hospitals are profiting off 340B

June 20, 2017

340B Spotlight: 340B hospitals continue to benefit from consolidation at expense of patients

April 27, 2017

New analysis: More than half of patients’ out-of-pocket spending for brand medicines is based on full list price

March 29, 2017

340B Spotlight: Audit findings show importance of increased oversight of 340B program

February 9, 2017

Fact Check: How hospitals continue to drive health care spending

Hospitals

Lets Talk About Cost

Fact Check: How hospitals continue to drive health care spending

December 3, 2020

Fact Check: How hospitals continue to drive health care spending

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