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Biopharmaceutical manufacturers change lives with groundbreaking medicines while supporting nearly 5 million U.S. jobs. A new report from TEConomy Partners highlights the positive impacts biopharmaceutical innovation has for state and regional economies in the U.S. In total, 47 states and Puerto Rico are involved in the manufacturing of FDA-approved medicines.  

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Biopharmaceutical companies and their supply chains are key contributors in supporting jobs and local economies across the country. The analysis shows that industry weathered economic downturns, demonstrating 30 percent growth from 2015 to 2022, providing vital stability to both the production of life saving medicines and to the U.S. and regional economies in which it operates. 

Economic Output  

  • The U.S. biopharmaceutical industry exceeded $800 billion in direct output in 2022 and contributed an additional $850 billion in output through its suppliers and other sectors of the economy, for a total of more than $1.65 trillion. This combined, total output impact represents 3.6 percent of all U.S. output. 
  • The biopharmaceutical sector and its supply chain generated at least $1 billion in economic output in each of 48 states, as well as Puerto Rico and the District of Columbia. 
  • California alone generated more than $276 billion in economic output thanks to the biopharmaceutical industry.  

American Jobs and Operations 

  • Biopharmaceutical workers are employed at more than 1,500 manufacturing facilities across 47 states, the District of Columbia and Puerto Rico 
  • Six states — California, Massachusetts, New Jersey, New York, North Carolina and Pennsylvania — each have more than 50,000 workers directly employed by the biopharmaceutical industry.
  • 24 states and Puerto Rico have an industry workforce exceeding 10,000 jobs.  
  • Six states have between 5,000 and 10,000 people in biopharmaceutical industry jobs. 
  • Compensation averages $157,712 annually per worker directly employed by the biopharmaceutical sector, more than twice the national average across all industries.   

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To learn more about your state, visit our PhRMA.org/States.  

Tim McClung

Tim is a director of policy & research at PhRMA.

Tim McClung

Staffing up: Building the future biopharma workforce to keep America in the lead

June 29, 2026

Insurers are blaming medicines for premium hikes in Massachusetts. The state's own data suggests otherwise.

June 24, 2026

MFN price controls threaten American jobs and the U.S. economy

May 28, 2026

340B is growing, but it is unclear if Illinois patients benefit

May 27, 2026

State price-setting boards create more questions than answers

May 20, 2026

States should avoid repeating the IRA’s price‑setting mistakes 

April 21, 2026

Virginia should be cautious about importing federal price-setting mechanisms

April 1, 2026

New report from Minnesota: 340B is generating billions for big hospitals

March 9, 2026

America Cures: Championing U.S. leadership in medical innovation

February 18, 2026

50-state poll says Americans are concerned that hospital markups hurt patients

January 27, 2026

California’s landmark PBM crackdown: A wake-up call for reform

November 13, 2025

Middlemen mark up drug prices and keep discounts meant for you

November 10, 2025

Celebrating STEM Day: Investing in America’s innovators

November 8, 2025

Manufacturing U.S. jobs and breakthroughs

October 6, 2025

Historic biopharmaceutical investments: A prescription for America’s future

September 29, 2025

Why states struggle to deliver savings: Middlemen and 340B siphon dollars from patients and states

September 15, 2025

Medical innovation takes center stage in state legislatures

August 27, 2025

North Carolina puts patients first with rebate pass-through law

July 29, 2025

How the 340B hospital markup program could hurt Michigan patients

June 12, 2025

Strong Trade Policies Protect American Workers and Biopharmaceutical Innovation

March 12, 2025

New research: Industry sponsored clinical trials contribute billions to state economies

March 6, 2025

Virginia, Don't Let Politicians Take Away Your Medicine

January 23, 2025

7 reasons why states shouldn’t copy the IRA’s price setting mistake

October 15, 2024

Three ways state drug price setting boards fail patients

September 18, 2024

Industry-backed STEM programs have supported 111 million students and nearly 183,000 teachers

August 1, 2024

Government price-setting boards: Why Minnesota needs to take a better approach

May 9, 2024

Insurance data: PBM reform has no material impact on premiums

April 24, 2024

Government price setting won’t help patients in Illinois

April 22, 2024

Colorado is proof: Too many unanswered questions remain about state government price setting's impact on patients and providers

March 14, 2024

The truth about Nebraska's price setting push

February 13, 2024

Biden Administration’s Indo Pacific trade dialogue is a missed opportunity to bolster American exports, innovation

November 29, 2023

ICYMI: Scott LaGanga and Matt Salo deliver a State of the Industry Report

October 25, 2023

4 truths about state government price setting

October 10, 2023

The Biden Administration has failed to advance an inclusive, worker-centered trade agenda

September 5, 2023

Three concerns about Colorado's approach to government price setting

August 23, 2023

Michigan proposal jeopardizes access to medicines

August 21, 2023

Four ways that America’s biopharmaceutical industry supports jobs and fuels economic growth

May 18, 2023

A win for Indiana patients: “Sharing the savings” legislation now law

May 8, 2023

U.S. biopharmaceutical exports support jobs, innovation

March 20, 2023

ICYMI: New research builds upon growing body of evidence on value of COVID-19 treatments and vaccines

August 16, 2022

The Senate’s latest price setting proposal will undermine U.S. economic growth

August 3, 2022

ICYMI: A patient, physician, biotech investor and industry leaders warn about the dangers of government price setting bill

July 29, 2022

PhRMA member companies’ R&D investments reach record high of $102.3 billion in 2021

July 18, 2022

Putting patients first at the state level — A conversation with Mark Reisenauer, President of Astellas Pharma US

July 14, 2022

COVID-19 vaccines and treatments helped save millions of lives and billions in health care costs

July 7, 2022

Biopharmaceutical industry drives economic growth in all 50 states

March 14, 2022

PhRMA member companies’ R&D investments reach record high of $91.1 billion in 2020

July 22, 2021

Data shows COVID-19 vaccines are creating a pathway to a strong U.S. recovery

July 2, 2021

Beyond output and employment: The impact of America’s biopharmaceutical industry

February 11, 2021

Preserving U.S. innovation worldwide is more important than ever

January 29, 2021

American biopharmaceutical manufacturing: Fueling economic growth now and for years to come

December 21, 2020

Manufacturing Day 2020: A closer look at the biopharmaceutical industry’s contributions

October 2, 2020

America’s global leadership in biopharmaceutical manufacturing

June 4, 2020

New report: Biopharmaceutical industry supports over 4 million jobs and $1.1 trillion in U.S. economic output

February 12, 2020

What you need to know about H.R. 3

December 12, 2019

New poll: 76% of voters concerned Speaker Pelosi’s plan would result in fewer new medicines

December 5, 2019

IP Explained: By the Numbers: How reliable IP protections promote a strong U.S. economy

November 4, 2019

What they are saying: Negative impact of Pelosi’s plan on biopharmaceutical innovation

October 31, 2019

Pelosi’s radical plan leaves lung cancer patients behind

October 23, 2019

Event tomorrow: Maintaining America’s leadership in access and innovation

October 16, 2019

Pelosi’s radical plan would leave Alzheimer’s patients behind

October 16, 2019

What they are saying: Broad opposition to Pelosi’s radical drug pricing plan

October 10, 2019

On Manufacturing Day, a closer look at the biopharmaceutical sector’s contributions

October 4, 2019

By the Numbers: Pelosi’s radical plan puts America’s economy and jobs at risk

September 26, 2019

World Trade Month: How we can expand world-class pro-innovation standards

May 22, 2019

New Report: Advanced manufacturing powering innovative biopharmaceuticals

May 10, 2019

Clinical trials impact state economies

May 3, 2019

Biopharmaceutical venture capital is spurring innovation and economic growth

February 11, 2019

PhRMA member companies R&D investments hit record high in 2017 - $71.4 billion

August 9, 2018

Researchers bring focus on science and medicine to California’s capital city

May 29, 2018

To continue to drive the innovation economy and exports, American biopharmaceutical sector depends on fair trade agreements

May 10, 2018

New Report: America's biopharmaceutical industry supports 4.7 million jobs

March 1, 2018

New PhRMA resources chock full of biopharma industry facts

July 20, 2017

New medicines are part of the solution to hold down future health care costs

June 28, 2017

Biopharmaceutical industry supports jobs and drives economic growth across the United States

Economic Impact

State Policy

Biopharmaceutical industry supports jobs and drives economic growth across the United States

May 16, 2024

Biopharmaceutical industry supports jobs and drives economic growth across the United States

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