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The 340B Drug Pricing Program has grown yet again, exceeding $100 billion in sales in 2022 when 340B-priced medicines are measured at wholesale acquisition cost. Recent data from IQVIA shows 340B grew 12.2% year-over-year in 2022, continuing a trend in which 340B sales have almost doubled since 2018, outpacing growth of the total U.S. drug market.

If the 340B program was functioning as Congress intended, this growth would be a good thing for vulnerable patients. However, there is little to no evidence 340B is always providing patients with access to affordable health care and medications they need. Instead, it has devolved into a program that’s less about patients and more about boosting the bottom lines of hospitals, for-profit pharmacies and pharmacy benefit managers (PBMs).

Eligible hospitals can buy deeply discounted 340B medicines and then charge patients higher prices — all while pocketing the difference. There is no requirement that 340B hospitals pass along discounts to patients or report how they use the profits to help patients access medicines.

This latest report makes clear that, without meaningful action from Congress to get 340B back on track and working for the patients who need it most, the program will continue to grow exponentially while leaving patients behind.

Learn more at PhRMA.org/340B.

Nicole Longo

Nicole Longo is Deputy Vice President of public affairs at PhRMA focusing on Medicare, 340B, importation and more. She previously worked for a D.C.-based public affairs firm where she assisted a wide range of clients with communications efforts on everything from trade policy to agriculture policy to health care policy. Outside the office, Nicole can be found trying new restaurants (usually Italian), taking an occasional barre class and cheering on the Cincinnati Bengals.

Nicole Longo

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As football season kicks off, hospitals keep scoring on 340B

September 9, 2026

ICYMI: Hospital consolidation is driving up health care costs

August 27, 2026

It's time to modernize 340B: The case for a rebate model

August 19, 2026

ICYMI: Fox business hosts call 340B a ‘Rotten System’ and ‘Cash Cow’ for hospitals

July 23, 2026

340B’s reality: A booming business for hospitals, pharmacies and corporate giants

June 25, 2026

340B’s lack of guardrails lets big hospital systems turn it into an oversight-free revenue stream

June 22, 2026

Private equity's new play? Become a nonprofit to profit off 340B.

June 5, 2026

340B is growing, but it is unclear if Illinois patients benefit

May 27, 2026

Fox Business spotlights hospitals abuse of the 340B program

May 15, 2026

The Wall Street Journal raises new alarms about 340B

May 11, 2026

Hospitals in the hot seat: Congress sharpens focus on 340B, consolidation and rising costs

May 7, 2026

New "Goldmine” ad reveals hospitals hide how they profit from 340B markups

May 6, 2026

A program off track: How 340B drives both hospital consolidation and system gaming

April 27, 2026

Washington Post Editorial Board says 340B has become “corporate welfare”

April 27, 2026

Modernizing 340B using rapid verification: The case for a rebate model 

April 20, 2026

Congress should look under the hood of 340B, hospitals don't want them to

March 19, 2026

340B hospitals buy low and sell high, a new analysis shows

March 12, 2026

New report from Minnesota: 340B is generating billions for big hospitals

March 9, 2026

340B hospital markup scheme is costing states, taxpayers billions

February 25, 2026

Questions mount over 340B program and increased cost to everyone

February 23, 2026

PhRMA Forum 2026 highlights the importance of fostering the next era of American leadership

February 18, 2026

50-state poll says Americans are concerned that hospital markups hurt patients

January 27, 2026

New analysis finds 340B hospitals push patients toward costly care to boost profits

January 21, 2026

Data shows tax-exempt hospital profit-seeking behavior, not drug prices, is driving explosive 340B expansion

January 8, 2026

Big, tax-exempt hospitals are charging cancer patients, employers massive medicine markups

January 5, 2026

340B’s billion-dollar boom: Oversight lags as spending soars

December 19, 2025

New study: 340B rebate model pilot won’t hurt cash flow for providers

December 18, 2025

One thing the Senate can agree on: It’s time to fix 340B

November 25, 2025

Middlemen mark up drug prices and keep discounts meant for you

November 10, 2025

The Administration approves manufacturers’ 340B rebate pilot plans

November 6, 2025

340B abuses are fueling higher Medicare costs, new BRG report shows

October 15, 2025

ICYMI: The Wall Street Journal calls 340B reform a “good idea to cut drug costs”

September 23, 2025

340B hospitals use scare tactics to evade accountability

September 16, 2025

Why states struggle to deliver savings: Middlemen and 340B siphon dollars from patients and states

September 15, 2025

CBO: 340B program costs taxpayers, no evidence patients benefit

September 10, 2025

PhRMA stresses importance of 340B Rebate Model Pilot

September 9, 2025

New “Meet Mark” ad exposes how the 340B hospital markup program drives up costs for everyone

September 3, 2025

New study unmasks how big-city hospitals exploit 340B by posing as rural providers

August 21, 2025

Study: 340B hospitals drive up patient drug costs

August 15, 2025

Curbing 340B abuse and rising costs with the rebate model

August 12, 2025

The hidden cost of 340B: A multi-billion-dollar burden on taxpayers and Medicaid

July 14, 2025

Latest analysis from Ohio exposes growing abuses of the 340B markup program

July 7, 2025

New report finds rampant abuse of the 340B program

June 20, 2025

How the 340B hospital markup program could hurt Michigan patients

June 12, 2025

New “Balance the Scales” campaign highlights why Americans pay more for prescription medicines

May 21, 2025

How the 340B hospital markup program and PBMs drive up costs for U.S. patients

May 16, 2025

Foreign first pricing schemes don’t address why Americans pay more

May 15, 2025

When hospitals have free rein to mark up drug prices, who pays the price?

May 1, 2025

New report finds more abuse of 340B program by hospitals and drug middlemen

March 24, 2025

A closer look at how health care consolidation drives up patient costs, creates barriers to care

March 17, 2025

340B markup program is a hidden tax, increasing costs for employers, straining state and federal budgets

March 5, 2025

New report sheds light on payment flows in the pharmaceutical supply chain, including the role of 340B and vertical integration

February 13, 2025

Wrapping up the J.P. Morgan Healthcare Conference

January 16, 2025

NYT exposes hospitals, middlemen make millions off a hospital markup program

January 15, 2025

PhRMA CEOs Tee Up Next Week's Health Care Conference

January 11, 2025

New study: Entities that don’t make medicines get half of what is spent on those medicines

January 7, 2025

A new administration poses new opportunities for patient access

December 17, 2024

New 340B report from Minnesota exposes steep hospital markups on medicines, patient benefits remain unclear

November 27, 2024

Michigan hospitals using federal program to markup cost of medicines, gouging patients

November 27, 2024

340B spending is exploding, forcing prices up for patients, employers and government programs

November 13, 2024

Three things to know about 340B contract pharmacies

November 12, 2024

PhRMA urges HRSA not to impede new 340B pricing approaches to improve transparency and integrity

October 18, 2024

Illegal abuse of 340B hurts us all

October 3, 2024

340B sales go up, free or reduced-cost care offered at hospitals goes down

July 1, 2024

ICYMI: Health care policy should be driven by patients, not politics

June 10, 2024

The hidden bill patients don’t know they are paying

June 3, 2024

340B grows and grows, but patients do not see the savings

May 13, 2024

340B grows and grows, but patients do not see the savings

May 13, 2024

PBMs using 340B program to drive profits at patients’ expense

March 28, 2024

What’s the 340B program like in your state?

February 7, 2024

New year, same exploitation of the 340B program

January 25, 2024

How the 340B program became a PBM giveaway

December 11, 2023

New report adds to questions about nonprofit status of 340B hospitals

November 7, 2023

By the Numbers: 340B continues to climb in profits, dwindle with patient support

September 13, 2023

New 340B Mega Guidance

August 3, 2023

New report: Hospitals mark up medicine prices 500%

August 2, 2023

read more

August 2, 2023

PhRMA responds to Senate: Today’s 340B program leaves patients behind | PhRMA

July 28, 2023

New studies add to body of evidence questioning 340B efficacy

July 11, 2023

Nonprofit hospitals fall short on community benefit, studies show

April 24, 2023

Why Congress should prioritize fixing the 340B program

March 2, 2023

What they are saying: Nonprofit hospitals are gaming the system at the expense of patients

February 21, 2023

ICYMI: PhRMA kicks off the year at the 2023 J.P. Morgan Health Care Conference

January 19, 2023

340B program continues to drive shift in care to more expensive hospital settings

December 15, 2022

The 340B program is interfering with the U.S. biosimilars market and impacting patient costs

November 21, 2022

Three ways 340B is failing vulnerable patients

October 20, 2022

If patients aren’t benefiting from the 340B program, who is?

October 6, 2022

New data: The 340B program is driving up costs for patients and our health care system

September 15, 2022

Word of the Month: 340B covered entity

August 29, 2022

340B program remains second largest federal drug program, yet little solid evidence of benefits to patient

June 30, 2022

Study after study after study: Contract pharmacy expansion not aligned in communities 340B is meant to serve

June 24, 2022

New research finds gaps in charity care provided by 340B hospitals

June 2, 2022

By the numbers: Contract pharmacy participation in the 340B program

March 31, 2022

340B 101: Three charts show the program maximizes hospitals’ bottom line with little consideration for patients

February 8, 2022

New study finds more than half of brand medicine spending goes to the supply chain and others

January 7, 2022

Making medicines more affordable: Preserving safety-net programs like 340B

December 17, 2021

Fact Check: Do contract pharmacies help patients access 340B medicines? No.

November 2, 2021

New video: Why changes to the 340B program are essential for patients

October 28, 2021

New analysis adds to research questioning whether 340B is working as Congress intended

October 13, 2021

340B hospitals among those that provide lowest levels of community benefit across the country

July 27, 2021

Getting the 340B program back on track in 2021

March 10, 2021

Correcting the record: Biopharmaceutical companies remain committed to the 340B program and helping patients

December 17, 2020

PhRMA submits comments on ways to refocus the 340B program on America’s vulnerable patients

November 2, 2020

340B hospitals and for-profit pharmacies generating significant revenue from program meant to help needy patients

October 23, 2020

Growth in 340B program has not translated to improvements for patients

October 5, 2020

New GAO report: Some hospitals participating in 340B may not be eligible for the program

January 14, 2020

Nearly 50% of brand medicine spending goes to the supply chain and others

January 9, 2020

340B Spotlight: How for-profit middlemen are taking advantage of a program meant to support nonprofit entities and patients

August 20, 2019

Study finds hospitals continue to mark up medicines up to 500% of their cost

July 9, 2019

Fresh data show, yet again, 340B is growing while charity care dwindles at many 340B hospitals

May 16, 2019

New study finds hospitals continue to push patients to costlier outpatient settings

May 13, 2019

340B continues to drive shift in site of care for physician-administered medicines to more expensive hospital settings

April 5, 2019

New study finds hospitals prescribe more medicines, and more expensive medicines, after joining 340B program

December 18, 2018

New study finds some hospitals mark up medicine prices at least 700 percent

September 5, 2018

New analysis finds 340B medicine sales hit record high in 2017 and continue to grow as a share of total drug spending

August 20, 2018

PhRMA submission to HHS on blueprint to lower drug prices and reduce out-of-pocket costs

July 16, 2018

GAO again recommends improvements to 340B program

July 11, 2018

ICYMI: Analysis finds higher outpatient drug spending at 340B hospitals

June 18, 2018

New 340B analysis: Hospitals raking in billions while uncompensated care drops by billions

May 15, 2018

340B Spotlight: How much money are hospitals pocketing under 340B and what are they doing with those profits?

March 28, 2018

340B Spotlight: Hospital system adds voice to comments about flawed 340B program

February 2, 2018

Fact Check Friday: The truth about the cost of 340B to patients

January 26, 2018

340B Spotlight: New pieces of legislation continue momentum to fix 340B program

January 18, 2018

340B Spotlight: ICYMI – 340B hearing, new reports highlight growing need for program reform

October 20, 2017

How much are hospitals marking up the price of medicines? The answer may surprise you.

October 17, 2017

340B Spotlight: New analysis finds 340B program growth continues to accelerate despite false claims

July 13, 2017

340B Spotlight: ICYMI – AJC looks at how some Georgia hospitals are profiting off 340B

June 20, 2017

340B Spotlight: 340B hospitals continue to benefit from consolidation at expense of patients

April 27, 2017

340B Spotlight: Audit findings show importance of increased oversight of 340B program

February 9, 2017

"340B program reaches $100 billion in sales, while patients are left behind"

340B

340B program reaches $100 billion in sales, while patients are left behind

June 14, 2023

"340B program reaches $100 billion in sales, while patients are left behind"

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