Cystic Fibrosis: Then & Now

Recent Advances Attack Both the Symptoms and Cause of the Disease

Cystic fibrosis (CF) is a life-threatening, genetic disease where the body produces an accumulation of thick, sticky mucus that clogs the lungs, pancreas, and other organs. In the lungs, this mucus blocks airways and results in a persistent cycle of inflammation, chronic bacterial infection, severe lung damage, and sometimes respiratory failure. In the pancreas, this mucus obstructs the movement of digestive enzymes that are important for helping the body to break down food and absorb nutrients.

CF Inline

An estimated 30,000 children and adults in the United States have CF, and each year 1,000 new cases are diagnosed. In the last 30 years, the life expectancy of a child with CF has doubled, due in part to treatment advances. A recent report examines the important therapeutic gains that have been made for patients in the last decade.