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Cancer medicines cost nearly twice as much in hospital outpatient facilities than in physician offices in the commercial market, according to a new study from the Employee Benefit Research Institute Center for Research on Health Benefits Innovation. These cost differences were not driven by a difference in the severity of illness, but were driven by hospital pricing practices.

Cancer Medicines Cost Nearly Twice as much-1-1

The study also found:

  • Hospital outpatient facilities charged 1.3 to 4.3 times more than physician offices for cancer medicines. 

  • Employers and payers could save $9,766 per covered cancer patient in just one year if they paid physician office prices rather than hospital outpatient facilities prices for physician-administered cancer medicines. 

  • Employers could cut their medicine costs nearly in half without affecting quality of care if patients shifted toward physician offices, since nearly half of oncology therapy takes place in hospital outpatient facilities.

This study underscores just how much hospitals are driving health care spending in the United States by marking up medicines. A recent analysis found hospitals charge, on average, five times their cost for medicines, driving up cost sharing and premiums for patients across the country.

To learn more, read the study here and visit www.LetsTalkAboutCost.org. 

Katie Koziara

Katie Koziara is Senior Director of public affairs at PhRMA focusing on the organization’s executive visibility work and media relations strategy. She previously ran the social media strategy for a D.C.-based non-profit working on federal management and leadership issues. Katie earned her B.A. in Public Policy from the University of Michigan’s Ford School and is currently earning her M.A. in Fiction Writing from Johns Hopkins University.

Katie Koziara

ICYMI: Hospital consolidation is driving up health care costs

August 27, 2026

New study: HPV vaccination helps prevent cervical cancer deaths

July 21, 2026

340B’s reality: A booming business for hospitals, pharmacies and corporate giants

June 25, 2026

America's cancer research progress is real and worth protecting

May 28, 2026

Ahead of ASCO: Cancer innovation is promising, but policy choices matter

May 26, 2026

A program off track: How 340B drives both hospital consolidation and system gaming

April 27, 2026

Washington Post Editorial Board says 340B has become “corporate welfare”

April 27, 2026

Hospitals drive nearly 80% of the U.S. health spending gap

March 25, 2026

Congress should look under the hood of 340B, hospitals don't want them to

March 19, 2026

340B hospitals buy low and sell high, a new analysis shows

March 12, 2026

New report from Minnesota: 340B is generating billions for big hospitals

March 9, 2026

Advancing patient care: A look at new medicines approved in 2025

January 30, 2026

CAREs 2025: Supporting community-based solutions that improve access to medicines

January 22, 2026

New analysis finds 340B hospitals push patients toward costly care to boost profits

January 21, 2026

Price setting policies put cancer gains in jeopardy

January 16, 2026

Latest analysis from Ohio exposes growing abuses of the 340B markup program

July 7, 2025

Improved treatments continue to lead to declining cancer mortality rates in the U.S.

February 25, 2025

Guest Perspective: Prioritize Innovative Care

February 11, 2025

Preventing and fighting disease: A look at the biopharmaceutical progress made for patients in 2024

February 3, 2025

Post-approval R&D is critical for fighting cancer. The IRA makes it more difficult.

November 13, 2024

The importance of partnership: A conversation with Takeda

October 10, 2024

The future of oncology R&D lies in policymakers’ hands

July 8, 2024

Showcasing the promise of biopharma at ASCO 2024

June 28, 2024

Critics repeat same, misleading narrative on potential “costs” of new medicines

May 7, 2024

Championing cancer equity: Our drive for healthier AANHPI communities

May 1, 2024

Insurance data: PBM reform has no material impact on premiums

April 24, 2024

What recent rhetoric on the cost of diabetes and anti-obesity medicines gets wrong

April 9, 2024

3 Takeaways from POLITICO’s Health Care Summit

April 3, 2024

The impact of innovative medicines: A caregiver's perspective

March 26, 2024

PhRMA awards $250,000 to community-based projects to improve equitable cancer outcomes

February 9, 2024

Setting the Record Straight: Comparing U.S. drug prices to those in foreign countries hurts patients

February 7, 2024

Three things to know about antibody drug conjugates

February 2, 2024

When it comes to the future of innovation, the ball is in policymakers’ court

January 22, 2024

The IRA’s pill penalty threatens the future of oncology R&D

November 16, 2023

New Report: 1,600 cancer treatments and vaccines in clinical development

November 9, 2023

R&D leaders to Biden Administration: Your policies are undermining the Cancer Moonshot

October 18, 2023

By the Numbers: 340B continues to climb in profits, dwindle with patient support

September 13, 2023

Watch: New video series spotlights advances in biopharmaceutical science

August 24, 2023

AARP’s latest misleading report

August 11, 2023

New report: Hospitals mark up medicine prices 500%

August 2, 2023

read more

August 2, 2023

Key considerations as Congress works towards PAHPA reauthorization

July 12, 2023

Between hope and despair: Improving cancer outcomes

July 11, 2023

New report shows high-impact R&D happens after cancer medicines are first approved

July 10, 2023

New report shows how the Inflation Reduction Act stifles innovation for small molecule medicines

June 22, 2023

ASCO 2023: Protecting our progress in the fight against cancer

June 15, 2023

Highlights from ASCO 2023

June 8, 2023

Insulin: Key Facts on Access & Affordability

May 10, 2023

4 key facts on medicine prices and spending

May 9, 2023

Three facts about health care spending

April 25, 2023

Nonprofit hospitals fall short on community benefit, studies show

April 24, 2023

IRA Impacts: Cancer treatment research and development

March 23, 2023

Why Congress should prioritize fixing the 340B program

March 2, 2023

What they are saying: Nonprofit hospitals are gaming the system at the expense of patients

February 21, 2023

State policymakers can protect American innovation and help Americans live longer, healthier lives

February 9, 2023

ICYMI: Cancer death rate continues to decline due to treatment advances

January 25, 2023

Novel medicines approved in 2022 offer increased treatment options for patients

January 23, 2023

ICYMI: PhRMA kicks off the year at the 2023 J.P. Morgan Health Care Conference

January 19, 2023

Study finds hepatitis C cure saved Medicaid $15 billion

January 5, 2023

340B program continues to drive shift in care to more expensive hospital settings

December 15, 2022

Stories from the lab: Researchers discuss innovative treatments for cancers of the blood

December 1, 2022

New data show how insurers and middlemen shift Rx costs onto patients

November 16, 2022

ICYMI: PhRMA COO Lori Reilly Esq. speaks with Jacob Van Naarden about the future of cancer research

November 8, 2022

Protecting treatment advances for breast cancer

October 31, 2022

Busting 3 Myths About Copay Coupons

October 5, 2022

Making coupons count for patients at the pharmacy counter

August 25, 2022

By the Numbers: Patients lose when the government sets prices

July 8, 2022

Prescription drug prices are not fueling inflation

July 6, 2022

Key takeaways from ASCO's annual meeting

June 10, 2022

PhRMA warns of the growing influence of middlemen over patient access and out-of-pocket costs for patients

May 31, 2022

Report finds PBMs are increasingly restricting patient access to medicines

May 25, 2022

ICYMI: First pediatric patient to receive CAR-T cell therapy celebrates 10 years of being cancer-free

May 25, 2022

Report: More than 500 medicines in development to treat disorders of the blood

May 18, 2022

ICYMI: PhRMA CEO Stephen J. Ubl spotlights lessons learned during COVID-19

May 13, 2022

Annual projections from NHE compared to actual health care spending

May 5, 2022

What’s really happening when it comes to prescription drug costs

April 27, 2022

Analysis: States can help patients save nearly $1,000 annually on their medicines

April 21, 2022

New analysis confirms hospitals markup prices for oncology therapies

April 21, 2022

How standardized plans can improve patients’ access to medicines

April 18, 2022

Correcting the record: Putting medicine costs and spending in context

March 24, 2022

Sharing rebates can save Americans with diabetes 500 each year and improve adherence

March 16, 2022

Guest Post: If we truly want to cure complex diseases, politicians should reject price setting

March 14, 2022

Veterans Affairs 101: Three charts show how the VA system differs from Medicare

March 11, 2022

If drug prices are growing below the rate of inflation, why are patients still feeling the sting at the pharmacy?

March 8, 2022

4 things to know about biopharmaceutical efforts to fight cancer

February 24, 2022

Government price setting leaves behind families counting on new medicines

February 23, 2022

340B 101: Three charts show the program maximizes hospitals’ bottom line with little consideration for patients

February 8, 2022

Research and development continues long after a medicine is initially approved

February 1, 2022

New poll of all 50 states and 435 Congressional Districts shows perils of so-called Medicare “negotiation”

January 25, 2022

CBO reaffirms our innovation ecosystem leads to improved lives, long-term savings

January 21, 2022

New data show continued decline in death rates for cancer patients related to treatment advances

January 20, 2022

New study finds more than half of brand medicine spending goes to the supply chain and others

January 7, 2022

New NHE data show the true picture of health care spending

December 22, 2021

3 things to know about the importance of post-approval research and development

December 6, 2021

Guest post: Congress should not put future innovation at risk

November 29, 2021

What is missing in the current drug pricing plan

November 23, 2021

ICYMI: PhRMA CEO speaks at STAT Summit about government price setting

November 19, 2021

In the current health care debate, Congress has lost sight of what matters to U.S. voters

November 15, 2021

CMS finds medication adherence saved Medicare up to 46.6B in avoided health care costs between 2013 and 2018

October 19, 2021

ICYMI: New study confirms policies like H.R. 3 could significantly reduce drug development

October 18, 2021

New poll shows Americans reject Medicare negotiation once they learn more about the policy

October 15, 2021

To drive up profits, hospitals continue unnecessary medicine mark-ups, burdening patients, employers and health care system

October 14, 2021

What is Kaiser Family Foundation up to?

October 12, 2021

Recognizing National Immunization Awareness Month

August 31, 2021

Recognizing Hepatitis R&D on World Hepatitis Day

July 28, 2021

340B hospitals among those that provide lowest levels of community benefit across the country

July 27, 2021

New reports shed light on key facts about medicines and affordability

June 8, 2021

How strengthening the biosimilar marketplace benefits patients

May 18, 2021

New report demonstrates development of new medicines relies on private sector expertise and investment

May 10, 2021

New data from insurers show detriments of copay accumulator adjustment programs

April 28, 2021

West Virginia becomes the first state to lower patient costs by sharing the savings

April 20, 2021

Getting the 340B program back on track in 2021

March 10, 2021

Nearly 40% of commercially insured patients face half their annual out-of-pocket expenses from just one health care encounter

March 2, 2021

Top five issues voters want addressed in the administration’s first 100 days

February 18, 2021

Action needed to preserve the six protected classes

February 3, 2021

Insurers shift medicine costs to patients with severe chronic illnesses

February 1, 2021

The new Administration should reconsider a recent HHS rule that could negatively impact patient access and affordability

January 27, 2021

New insulin report highlights how incentives benefit middlemen, harm patients

January 22, 2021

ICYMI: Cancer death rate continues decline due to advances in treatment

January 19, 2021

New data show retail medicine prices fell in 2019

January 13, 2021

Correcting the record: Biopharmaceutical companies remain committed to the 340B program and helping patients

December 17, 2020

Report: More than 1,300 medicines and vaccines in development to help fight cancer

December 15, 2020

Fact Check: How hospitals continue to drive health care spending

December 3, 2020

Accumulator adjustment programs lead to surprise out-of-pocket costs and nonadherence, analysis finds

November 19, 2020

340B hospitals and for-profit pharmacies generating significant revenue from program meant to help needy patients

October 23, 2020

Study finds biopharmaceutical innovation is responsible for 35% of the increase in life expectancy from 1990 to 2015

October 21, 2020

Survey found insurance premiums grew faster than inflation in 2020

October 20, 2020

Study finds middlemen excluded nearly 850 medicines from formularies this year

September 17, 2020

Manufacturer cost-sharing assistance programs can save chronically ill patients hundreds to thousands of dollars annually

August 19, 2020

Commercial health plans have increased patients’ out-of-pocket costs by over 50% in some therapeutic areas

August 12, 2020

Commercial health plans transition from copays to coinsurance and deductibles has increased patient out-of-pocket costs

August 6, 2020

Four things to know about the IQVIA “Medicine Spending and Affordability in the U.S.” report

August 5, 2020

New data show commercially insured patients face increasingly high cost sharing for brand medicines

July 30, 2020

Payers subject 80% of new RA and MS patients to utilization management restrictions

July 22, 2020

New report explores setbacks that bring future cancer success stories

July 16, 2020

Study finds the pharmaceutical industry retains a smaller share of revenue than research-intensive industries

July 14, 2020

Guest Post: Takeda seeks ‘new normal’ for cancer research during the COVID-19 pandemic

June 24, 2020

ICYMI: Pharmacy benefit managers increasingly exclude medicines from formularies, restricting patient access

June 1, 2020

New rule makes it harder for patients to lower their out-of-pocket costs

May 20, 2020

ICYMI: Patients saved nearly $800,000 out of pocket through innovative contracting arrangements

April 20, 2020

Retail medicine spending to remain stable share of overall health care spending through next decade

April 16, 2020

PhRMA comments on HHS proposed rule on manufacturer cost-sharing assistance and accumulator adjustment programs

March 3, 2020

Addressing barriers that inhibit value-based contracts

February 21, 2020

Fact Check: HCCI analysis overstates medicine spending and prices

February 19, 2020

New GAO report: Some hospitals participating in 340B may not be eligible for the program

January 14, 2020

Nearly 50% of brand medicine spending goes to the supply chain and others

January 9, 2020

New NHE data: Medicine prices declined, and hospitals were biggest driver of health care spending in 2018

December 6, 2019

More evidence that medicine prices are growing at slowest rate in decades

October 4, 2019

The truth about the marketing and promotion of medicines

October 3, 2019

Survey shows out-of-pocket costs top health care concern for voters

October 2, 2019

Four reasons why the radical Pelosi Plan is the wrong approach

September 24, 2019

Hospitals make 9 times more than physicians’ offices on provider-administered medicines

September 10, 2019

340B Spotlight: How for-profit middlemen are taking advantage of a program meant to support nonprofit entities and patients

August 20, 2019

Three things to know about the Part D GAO report

August 16, 2019

Setting the record straight on international reference pricing

July 16, 2019

Four states adopt first-in-the-nation laws to protect patients from surprise insurer practices

July 15, 2019

New Let’s Talk About Cost TV ad asks: Why aren’t patients sharing in savings at the pharmacy counter?

July 9, 2019

Study finds hospitals continue to mark up medicines up to 500% of their cost

July 9, 2019

Three reasons why the latest Rx Savings Solutions analysis is misleading

July 2, 2019

"If Washington isn’t careful, we might leave innovation behind"

June 24, 2019

How the rebate rule would help reduce patients’ out-of-pocket costs

June 3, 2019

Fresh data show, yet again, 340B is growing while charity care dwindles at many 340B hospitals

May 16, 2019

Ask About Adherence: OIG proposed rule to reform the rebate system could improve adherence

May 15, 2019

New study finds hospitals continue to push patients to costlier outpatient settings

May 13, 2019

4 Things to know about the IQVIA “Medicine Use and Spending” report

May 9, 2019

Meet MAT: 5 things to know about PhRMA’s new “Medicine Assistance Tool”

May 9, 2019

Six policy solutions to help patients afford their insulin

April 9, 2019

PhRMA comments on OIG proposed rule to reform the rebate system

April 8, 2019

340B continues to drive shift in site of care for physician-administered medicines to more expensive hospital settings

April 5, 2019

Five key facts about the market for insulins

April 1, 2019

OIG proposed rule could help strengthen the Part D market

March 28, 2019

Rebate rule would help ensure seniors with diabetes don’t pay more for their medicine than their insurer

March 25, 2019

The PBM story you haven’t heard: Hidden fees quadrupled in two years

March 20, 2019

OptumRX: Sharing rebates with patients is “worth it”

March 18, 2019

New data show how sharing negotiated discounts could save certain patients hundreds of dollars at the pharmacy counter

February 25, 2019

What you need to know about the new NHE health spending projections

February 22, 2019

New study shows why insurers should share rebates with Medicare Part D beneficiaries on a mandatory basis

February 14, 2019

New IQVIA data show medicine prices grew just 1.5 percent in 2018

January 29, 2019

Health Affairs study misses the mark on medicine costs

January 28, 2019

New government data show medicine price growth continues to decline

January 18, 2019

10 things you should know about medicine spending and costs

January 2, 2019

New study finds hospitals prescribe more medicines, and more expensive medicines, after joining 340B program

December 18, 2018

Six key facts about the market for insulins

December 17, 2018

Americans want to know more than just the list price of a medicine—and we’re answering their call

October 15, 2018

What they are saying: PhRMA member executives on industry’s new approach to DTC television advertising

October 15, 2018

Coupons allow patients to remain on medicines in spite of high cost sharing and deductibles

October 4, 2018

Experts agree: the Bipartisan Budget Act changes to Medicare Part D jeopardize the program

September 24, 2018

Saving kids and dogs from shared cancers

September 17, 2018

What if a couple of small fixes could protect seniors in the donut hole and save them money on out-of-pocket costs?

September 13, 2018

New study finds some hospitals mark up medicine prices at least 700 percent

September 5, 2018

69 percent of patients abandon medicines when cost sharing is more than $250

August 23, 2018

New analysis finds 340B medicine sales hit record high in 2017 and continue to grow as a share of total drug spending

August 20, 2018

New analysis in Health Affairs reinforces one-third of medicine list price rebated back to supply chain

August 13, 2018

PhRMA submission to HHS on blueprint to lower drug prices and reduce out-of-pocket costs

July 16, 2018

GAO again recommends improvements to 340B program

July 11, 2018

New data show patients’ out-of-pocket costs are rising faster than their insurers’ costs

July 9, 2018

Pass-through rebates do not violate non-interference clause but they do increase savings for seniors

July 2, 2018

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