Then & Now: Chronic Lymphocytic Leukemia

New Era of Targeted Therapy Shift Treatment Paradigm

Chronic lymphocytic leukemia (CLL) is a rare form of blood cancer that typically progresses more slowly than acute types of leukemia. Affecting an estimated 3 out of 100,000 people in the United States, CLL most often occurs after middle age and rarely is found in children. In patients with CLL, abnormal lymphocytes are produced and accumulate in the body. This accumulation weakens the immune system, leading to a variety of symptoms, including swelling of the lymph nodes, debilitating fatigue, and an increase in fever and infections.