Improving Clinical Trial Diversity is Critical to Health Equity

Enhancing clinical trial diversity is a highly complex challenge that requires a community-based, multi-stakeholder approach.

Learn more about PhRMA’s efforts to address the systemic barriers that can deter underserved communities from participating in clinical trials, so that people who want to participate, can.



  • Knocking Down Systemic Barriers and Changing the Paradigm to Enhance Clinical Trial Diversity

    Changing the paradigm chart showing disparate sites on the left, steps taken in the middle, and a sustainable, connected network of sites on the right

    Since June of 2020, PhRMA has convened thousands of stakeholders as we have worked to explore a new potential infrastructure with diverse communities, health systems and academia that seeks to show proof of concept for a network of connected, community-rooted trial sites.

    With strong support from the biopharmaceutical industry, this effort seeks to create a sustainable, community-based infrastructure focused on clinical trial diversity

    Our Progress

    Clinical Trial Diversity

    Industry-Wide Principles To Enhance Diversity In Clinical Trial Participation

    PhRMA recently announced first-ever, industry wide principles on clinical trial diversity.

    Critical to enhancing clinical trial diversity is addressing the systemic barriers that can deter underserved communities from participating in clinical trials, so that people who want to participate, can.

    Clinical Trial Diversity

    Insights From Our Stakeholder Workshop

    In June 2021, 500+ health care and community members from over 150 organizations came together at PhRMA’s first stakeholder workshop focused on improving diversity in clinical trials.

    Take a look at the highlights from the in-depth conversations.

    Clinical Trial Diversity

    Five Key Strategies for Enhancing Diversity in Clinical Trials

    A recent report outlines five critical strategies for enhancing diversity in clinical trials and is based on more than a year of research and feedback from more than 500 stakeholders across 150+ organizations.

    Five Key Strategies:

    • Create a network of clinical trial sites in underserved communities.
    • Develop a diverse pool of investigators and staff.
    • Establish long-term relationships and invest in the community.
    • Engage the community in conversations.
    • Provide sustainable support and standardized platforms.

    Community Based Partnership

    Equitable Breakthroughs in Medicine Development

    Equitable Breakthroughs in Medicine Development (EQBMED) is a pilot program allowing participating institutions to partner with patients, providers, industry leaders, technical experts, and the community at large to bring clinical trials directly to underrepresented and underserved patients. EQBMED is funded and supported by a grant from Pharmaceutical Research and Manufacturers of America (PhRMA). 

    As we endeavor to push forward to change the future, we must first understand the past

    Colonization, slavery, segregation, systemic racism—these experiences continue to disproportionately impact underserved communities and have created a foundation of mistrust rooted in history

    Events like these lead to lasting mistrust and impact how communities of color approach health care. This mistrust, combined with social and economic barriers, is amplified when it comes to clinical trials. We are committed to working with communities to address this.

    Some of this history can be found here:

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    Here is a small sampling of formative events in U.S. history that have shaped the relationship communities of color have with medical research and the health care system. This list is by no means exhaustive, but we hope it helps pave the way for candid dialogue that guides our work on equity.

    Slavery (1619 - 1865)

    An illustration depicting a pair of manacles, commonly used to restrain enslaved people during slavery in the United States
    Illustration by Toya Beacham. Click here to learn more about the artist.

    Gynecological Experimentation On Enslaved Women (1845 - 1849)

    An illustration depicting a black woman, whose red headband and green dress are colorized amid an otherwise black and white illustration, kneeling on a raised platform, with the profile of a white man in the foreground barely visible on the side of the image
    Illustration by Toya Beacham. Click here to learn more about the artist.

    Closing Of Medical Schools and Exclusion Of Future Health Providers (1870)

    An illustration of a black man depicted from the shoulders down, wearing a three-piece suit, carrying a medical bag
    Illustration by Toya Beacham. Click here to learn more about the artist.

    Birth Control Experimentation in Puerto Rico (1930s - 1970s)

    An illustration depicting a black Puerto Rican woman holding a young child on her lap, with another child nearby.
    Illustration by Toya Beacham. Click here to learn more about the artist.

    The Tuskegee Syphilis Study (1932 - 1972)

    An illustration depicting a black man in common clothing of a farmer from 1930s America, centered in a group of other similarly dressed figures who are shown in outline only
    Illustration by Toya Beacham. Click here to learn more about the artist.

    Henrietta Lacks (1951)

    An illustration depicting Henrietta Lacks, wearing a suit, smiling, and with her hands on her hips
    Illustration by Toya Beacham. Click here to learn more about the artist.

    Radioactive iodine (1956 - 1957)

    An illustration of a steel barrel with a radioactive waste label, behind a medicine tablet resting on a steel tray
    Illustration by Toya Beacham. Click here to learn more about the artist.

    Resources

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