phrma logo

PhRMA

PhRMA Sites

Login

Explore Member-Only Resources

Access exclusive advocacy, policy, and research materials through the member site.

Login now

About

About

Our Agenda

Our Agenda

Policy Issues

We believe that patients should have access to innovative medicines.

Learn More

Innovation Ecosystem

Intellectual Property

Research & Development

Future of Medicine

Government Price Setting

International

Innovation Ecosystem

Patient Access & Affordability

PBMs & Middlemen

Hospitals and 340B

Insurance Coverage

Cost of Medicines

Medicare & Medicaid

Patient Access & Affordability

Resources

Our mission is to conduct effective advocacy for public policies that encourage the discovery of important, new medicines for patients by biopharmaceutical research companies.

Learn More

Resources

Resources

Newsroom

Newsroom

Blog

Blog

America's Medicines

PhRMA Foundation

PhRMA Foundation Logo

Voters for Cures

VotersForCures.org Logo

Working for Cures

workersforcures.org logo

This is Innovation

Innovation.org logo

View More

Search in PhRMA

Find resources, news, and articles related to policy issues and scientific innovation.

What are you looking for?

Most Recent

Policy Paper

Press

Blog

Report

Fact Sheet

Event

Resource

Pages

Leader

Author

Comment

not used title

not used title

340BSpotlight_Header-5Over the years, the non-partisan Government Accountability Office (GAO) has reviewed various aspects of the 340B program, finding areas for improvement and providing recommendations. The latest report from GAO focused on contract pharmacy arrangements, reiterating findings from previous oversight reports and revealing some new startling findings about hospitals and contract pharmacies in the 340B program. The report further highlighted the need for changes to 340B to improve program integrity and oversight.

Here are three points that stood out:

  1. Chain pharmacies make up the majority (75 percent) of contract pharmacies arrangements. Even among chain pharmacies, large chains are disproportionately likely to be contract pharmacies. GAO, found that “the five biggest pharmacy chains—CVS, Walgreens, Walmart, Rite-Aid, and Kroger—represented a combined 60 percent of 340B contract pharmacies, but only 35 percent of all pharmacies nationwide.” Meaning large, for-profit retail pharmacies are generating additional revenue through a program meant to support non-profit entities providing care to needy patients.
  1. Contract pharmacies are incentivized to partner with hospitals and fill prescriptions with certain types of medicines to increase revenue. GAO found that the fees paid to pharmacies varied greatly and noted that fees paid were often structured so that the contract pharmacies make more money prescribing brand medicines as compared to generics. In a recent news article about the GAO report, an economist and expert on 340B noted that this can create incentives to increase use of brand medicines, which can raise costs for patients and payers.
  1. Hospitals and their contract pharmacies are not always sharing the 340B discount with low-income, uninsured patients. As noted by GAO, “Federal grantees were more likely than hospitals to provide such discounts and to provide them at all contract pharmacies.” According to the data, less than half of hospitals surveyed provide 340B discounts to low-income, uninsured patients. Of those hospitals that do provide a discount, some said they still charge patients more than the 340B discounted price that they paid to acquire the medicine.

This GAO study sheds new light on how hospitals are taking advantage of contract pharmacy arrangements to generate additional revenue through 340B without ensuring that low-income patients are benefiting from manufacturer discounts. Drug Channels also took a closer look at the study and concluded “Some of the report’s most startling revelations confirm our worst fears about how hospitals and pharmacies are abusing the 340B program.”

The study goes a step further and recommends concrete steps policymakers could take to improve oversight and accountability in 340B. This report is just the latest in a string of reports from non-partisan experts like HHS Office of the Inspector General and academic journals like the New England Journal of Medicine. Over the past decade, these reports have brought to light the shortcomings in the current 340B program and ways the program needs to be improved to ensure it actually benefits patients. As conversations about ways to fix 340B continue today on Capitol Hill, let’s hope Congress recognizes the seriousness of GAO’s findings in this study.

Read the full GAO report and learn more about ways to fix 340B at PhRMA.org/340B.

Nicole Longo

Nicole Longo is Deputy Vice President of public affairs at PhRMA focusing on Medicare, 340B, importation and more. She previously worked for a D.C.-based public affairs firm where she assisted a wide range of clients with communications efforts on everything from trade policy to agriculture policy to health care policy. Outside the office, Nicole can be found trying new restaurants (usually Italian), taking an occasional barre class and cheering on the Cincinnati Bengals.

Nicole Longo

Author Twitter

Author LinkedIn

As football season kicks off, hospitals keep scoring on 340B

September 9, 2026

ICYMI: Hospital consolidation is driving up health care costs

August 27, 2026

It's time to modernize 340B: The case for a rebate model

August 19, 2026

ICYMI: Fox business hosts call 340B a ‘Rotten System’ and ‘Cash Cow’ for hospitals

July 23, 2026

GAO again recommends improvements to 340B program

340B Spotlight

340B

Hospitals

GAO again recommends improvements to 340B program

July 11, 2018

GAO again recommends improvements to 340B program

Stay current on policy making

Sign up for email updates and follow us on social. 

About

Our Agenda

Policy Issues

Resources

Blog

Contact Us

Privacy Policy

Terms of Service

Facebook

Facebook

X

Twitter X

LinkedIn

LinkedIn

Instagram

instagram logo

America's Medicines

PhRMA Foundation

Voters for Cures

Working for Cures

Innovation.org

Please type your email

Success!

You've been added to the list