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The 340B Drug Pricing Program has grown yet again, exceeding $100 billion in sales in 2022 when 340B-priced medicines are measured at wholesale acquisition cost. Recent data from IQVIA shows 340B grew 12.2% year-over-year in 2022, continuing a trend in which 340B sales have almost doubled since 2018, outpacing growth of the total U.S. drug market.

If the 340B program was functioning as Congress intended, this growth would be a good thing for vulnerable patients. However, there is little to no evidence 340B is always providing patients with access to affordable health care and medications they need. Instead, it has devolved into a program that’s less about patients and more about boosting the bottom lines of hospitals, for-profit pharmacies and pharmacy benefit managers (PBMs).

Eligible hospitals can buy deeply discounted 340B medicines and then charge patients higher prices — all while pocketing the difference. There is no requirement that 340B hospitals pass along discounts to patients or report how they use the profits to help patients access medicines.

This latest report makes clear that, without meaningful action from Congress to get 340B back on track and working for the patients who need it most, the program will continue to grow exponentially while leaving patients behind.

Learn more at PhRMA.org/340B.

Nicole Longo

Nicole Longo is Deputy Vice President of public affairs at PhRMA focusing on Medicare, 340B, importation and more. She previously worked for a D.C.-based public affairs firm where she assisted a wide range of clients with communications efforts on everything from trade policy to agriculture policy to health care policy. Outside the office, Nicole can be found trying new restaurants (usually Italian), taking an occasional barre class and cheering on the Cincinnati Bengals.

Nicole Longo

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ICYMI: Hospital consolidation is driving up health care costs

August 27, 2026

It's time to modernize 340B: The case for a rebate model

August 19, 2026

ICYMI: Fox business hosts call 340B a ‘Rotten System’ and ‘Cash Cow’ for hospitals

July 23, 2026

340B’s reality: A booming business for hospitals, pharmacies and corporate giants

June 25, 2026

"340B program reaches $100 billion in sales, while patients are left behind"

340B

340B program reaches $100 billion in sales, while patients are left behind

June 14, 2023

"340B program reaches $100 billion in sales, while patients are left behind"

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